“With Ananda microfluidic devices, we were able to simultaneously injure 120 parallel axons and follow the regeneration process in one dish. This significantly increased reproducibility and the amount of results obtained per culture. With a regular cell culture dish it would have taken at least 30 dishes and much more microscope time because all processes were entangled and with different sizes.”
Regular culture plate
With Ananda Devices
In the brain
Margaret was investigating axonal resistance to injury and needed uniform single axons to produce precise cause damage and evaluate regeneration at the single cell level.
Dr. Margaret Magdesian needed a way to ensure reproducibility of the specific impact of injury on cells, and also to trace and record the behavior of cells in response to specific stimuli over time.
For more details please refer to: Magdesian et al., Biophys J. 2012 and Magdesian et al., J. Neuroscience 2016