With Ananda microfluidic devices, Dr. Dalinda Liazoghli was able to grow DRG neurons for several weeks. She obtained robust axonal myelination and the formation of internodes. The devices allowed for easy access and identification of neurites as well as of the associated myelinating cells. These properties of the devices contribute to studies on the process of myelination and the effects of axonal damage on this process.
Without Ananda Devices
With Ananda Devices
In the CNS
To study myelination of DRG neurons, Dr. Liazoghli needed a co-culture cell system that facilitated the visualization of axons and the development of myelin in vitro. Regular cell culture dishes do not always allow for the growth of multiple long axons for many weeks that is ideal for myelination studies.
For more details please refer to: Liazoghli et al., ACS Chemical Neuroscience 2012.